Cardiovascular Inflammation Reduction Trial 

This research study will evaluate low-dose methotrexate (LDM), a widely used anti-inflammatory drug taken by millions of older individuals who have severe arthritis. LDM has been in wide clinical use for nearly 40 years, and doctors have noticed that people with arthritis taking LDM seem to have lower rates of heart disease. However, it is not known if LDM will prevent heart attacks and stroke among people who do not have arthritis, but like you, have had a prior heart attack or have had major blockages in more than one coronary artery.

You may be eligible to participate in CIRT since you have had a heart attack or multiple coronary blockages in the past and you have been diagnosed with either diabetes or a condition called “metabolic syndrome” which puts you at high risk for developing diabetes.  If you would like to learn more about participating in the study please call:

Lisa Johnson, RN, CCRP
Clinical Research Nurse
College of Osteopathic Medicine
Touro University California
ph: 707.638.5969