SELECTED RELEVANT PUBLICATIONS

• Schwarz J-M, Schutz Y, Froidevaux F, Acheson KJ, Jeanpretre N, Schneider H, Felber JP, Jequier E. Thermogenesis in men and women induced by fructose vs glucose added to a meal. Am J Clin Nutr 49:667-674, 1989.
• Schwarz J-M, Schutz Y, Piolino V, Schneider H, Felber JP, Jéquier E. Thermogenesis in obese women. effect of fructose vs glucose added to a meal. Am J Physiol 262:E394-E401, 1992.
• Schwarz J-M, Acheson KJ, Tappy L, Piolino V, Muller MJ, Felber JP, Jéquier E. Thermogenesis mechanisms and fructose metabolism in humans. Am J Physiol 262:E591-E598, 1992.
• Hellerstein MK, Neese RA, Schwarz J-M. Model for measuring absolute rates of hepatic de novo lipogenesis and re-esterification of free fatty acids. Am J Physiol 265:E814-E820, 1993.
• Romijn, JA, Chinkes D, Schwarz J-M, Wolfe RR. Lactate-pyruvate interconversion in blood: implications for in vivo tracer studies. Am J Physiol 266:E334-E340, 1994.
• Hellerstein MK, Benowitz NL, Neese RN, Schwarz J-M, Hoh R, Jacob P, Hsieh J, Faix D. Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers. J Clin Invest 93:265-272, 1994.
• Schwarz J-M, Neese RA, Dare D, Turner SM, Hellerstein MK. Short-term alterations in carbohydrate energy intake in humans. J Clin Invest 96:2735-2743, 1995.
• Neese RA, Schwarz J-M, Faix D, Turner S, Letscher A, Vu D, Hellerstein MK. Gluconeogenesis and intrahepatic triose phosphate flux in response to fasting or substrate loads. J Biol Chem   270(24):14452, 1995.
• Hellerstein MK, Neese RA, Schwarz J-M, Turner S, Faix D, Wu K. Altered fluxes responsible for reduced hepatic glucose production and gluconeogenesis by exogenous glucose in rats. Am J Physiol 272:E163-E172, 1997.
• Gastaldelli A, Schwarz J-M, Caveggion E, Traber L, Traber D, Rosenblatt J, Toffolo G, Cobelli C, Wolfe R. Modeling in physiology: Glucose kinetics in interstitial fluid can be predicted by compartmental modeling. Am J Physiol 272:E494-E505, 1997.
• Tappy L, Schwarz J-M, Schneiter P, Cayeux C, Revelly,J-P, Fagerquist CF, Jequier E, Chiolero R. Effects of isoenergetic glucose-based or lipid-based parenteral nutrition on glucose metabolism, de novo lipogenesis, and respiratory gas exchanges in critically ill patient. Crit Care Med 26 (5):860-867, 1998.
• Fagerquist CK, Schwarz J-M. Gas-phase acid/base chemistry and its effects on mass isotopomer abundance measurements of biomolecular ions. J Mass Spectrom 33:144-153, 1998.
• Tappy L, Berger M, Schwarz JM, McCamish M, Revelly JP, Schneiter P, Jequier E, Chiolero R. Hepatic and peripheral glucose metabolism in intensive care patients receiving continuous high- or low-carbohydrate enteral nutrition. JPEN 23:260-268, 1999.
• Schwarz J-M, Chiolero R, Revelly J-P, Cayeux C, Schneiter P, Jequier E, Chen T, Tappy L. Effects of enteral carbohydrates on de novo lipogenesis in critically ill patients. Am J of Clin Nutr 72:940-945, 2000.
• Loe YC, Bergeron N, Rodriguez N, Schwarz J-M. A gas chromatography mass spectrometry method to quantify blood hydroxycitrate concentration. Anal Biochem 292: 148-154, 2001.
• Noor M, Lo JC, Mulligan K, Schwarz J-M, Halvorsen R, Schambelan M, Grunfeld C. Metabolic effects of indinavir in healthy HIV seronegative men. AIDS 15:F11-F18, 4, 2001.
• Battilana P, Ornstein K, Minehira K, Schwarz J-M, Acheson K, Schneiter P, Burri J, Jequier E, Tappy L. Mechanisms of action of ß-glucan in postprandial glucose metabolism in healthy men. Eur J Clin Nutr 55 (5): 327-333, 2001.
• Lo JC, Mulligan K, Noor M, Schwarz J-M, Halvorsen RA, Grunfeld C, Schambelan M. The effects of recombinant human growth hormone on body composition and glucose metabolism in HIV-infected patients with fat accumulation. J Clin Endocrinol Metab 86:3480-3487, 2001.
• Minehira K, Novel-Chate V, Schwarz J-M, Gillet M, Darioli R, Chiolero R, Tappy L. Hepatic de novo lipogenesis after liver transplantation. JPEN 25:229-235, 2001.
• Noor M, Lo JC, Mulligan K, Schwarz J-M, Halvorsen R, Schambelan M, Grunfeld C.
• Metabolic effects of indinavir in healthy HIV seronegative men. AIDS 15: F11-F18, 2001.
• Schwarz J-M, Mulligan K, Lee J, Lo JC, Noor M, Wen M, Grunfeld C, Schambelan M. The effects of recombinant human growth hormone on hepatic lipid and carbohydrate metabolism in HIV-infected patients with fat accumulation. J Clin Endocrinol Metab 87: 942-945, 2002.
• Trimmer JK, Schwarz JM, Casazza GA, Horning MA, Rodriguez N, Brooks GA.   Measurement of gluconeogenesis in exercising men by mass isotopomer distribution analysis. J Appl Physiol 2002 93:233-241, 2002.
• Noor MA, Seneviratne T, Aweeka F, Lo JC, Schwarz J-M, Mulligan K, Schambelan M, Grunfeld C. The HIV protease inhibitor indinavir acutely inhibits insulin-stimulated glucose disposal. A randomized, placebo-controlled study. AIDS 16:F1-F8, 2002.
• Minehira K, Tappy L, Chioléro R, Vladomira V, Berger MM, Revelly J-P, Schwarz J-M. Fractional hepatic de novo lipogenesis in healthy subjects during near-continuous oral nutrition and bed rest. A comparison with published data in artificially fed, critically ill patients. Clin Nutr 21: 345-350, 2002.
• Schwarz J-M, Linfoot PA, Dare D, Aghajanian K. Hepatic de novo lipogenesis in normo and hyperinsulinemic subjects consuming high-fat/low-carbohydrate and low-fat/high-carbohydrate isoenergetic diets. Am J Clin Nutr 77: 43-50, 2003.
• Lee G, Seneviratne T, Noor MA, Lo JC, Schwarz J-M, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C.  The metabolic effects of lopinavir/ritonavir in HIV-negative men.  AIDS 18:641-649, 2004.
• Lee GA, Mafong DD, Noor MA, Lo JC, Mulligan K, Schwarz J-M, Schambelan M, Grunfeld C. HIV protease inhibitors increase adiponectin in HIV-negative men. J Acquir Immune Defic Syndr 36:645-647, 2004.
• Lo JC, Mulligan K, Noor MA, Lee GA, Schwarz J-M, Grunfeld C, Schambelan M. The effects of low dose growth hormone in HIV-infected men with fat accumulation: a pilot study. Clin Infect Dis 39:732-735, 2004.
• Schwarz J-M, Lee GA, Park S, Noor MN, Lee J, Wen M, Lo JC, Mulligan K, Schambelan M, Grunfeld C. Indinavir increases glucose production in healthy HIV-negative men. AIDS 18:1852-1854, 2004.
• Faeh D, Minehira K, Schwarz J-M, Periasamy R, Park S, Tappy L. Effect of fructose supplementation and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy males. Diabetes 54:1907-1913, 2005.
• Tappy L, Berger MM, Schwarz J-M, Schneiter P, Kim S, Revelly JP, Chiolero R. Metabolic effects of parenteral nutrition enriched with n-3 PUFA acids in critically ill patients. Clin Nut 25(4):588-95, 2006.
• Lee GA, Mafong DD, Lo JC, Schwarz J-M, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C. Single-dose lopinavir/ritonavir acutely inhibits insulin-mediated glucose disposal in healthy normal volunteers. Clin Infect Dis.; 43: 658-660, 2006.
• Lee GA, M Rao, K Mulligan, JC Lo, F Aweeka, J-M Schwarz, M Schambelan, and C Grunfeld. Effects of Ritonavir and Amprenavir on Insulin Sensitivity in Healthy Volunteers. AIDS 21(16):2183-90, 2007.
• Mulligan K, Khatami H, Schwarz J-M, Sakkas GK, DePaoli AM, Tai VW, Wen MJ, Lee GA, Grunfeld C, Schambelan M. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with HIV-associated lipoatrophy and hypoleptinemia. J Clin Endocrinol Metab 94:1137-1144, 2009.
• K Stanhope^#, Schwarz^# J-M, NL Keim, SC Griffen, AA Bremer, JL Graham, B Hatcher, CL Cox, A Dyachenko, J cGahan, A Seibert, RM Krauss, S Chiu, EJ Schaefer, M Ai, S Otokozawa, K Nakajima, T Nakano, C Beysen, MK Hellerstein, L Berglund, PJ Havel. Effects of consuming fructose- or glucose-sweetened beverages for 10 weeks on lipids, insulin sensitivity and adiposity. J Clin Invest 119(5):1322-34 2009 (# co–first authors).
• Lee GA, Schwarz J-M, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C. The Acute Effects of HIV Protease Inhibitors on Insulin Suppression of Glucose Production in Healthy HIV-Negative Men. J Acquir Immune Defic Syndr 52(2):246-8, 2009.
• Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz J-M, Mulligan K, Schambelan M, Grunfeld C. The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers. AIDS 24(2):265-70, 2010.
• Campos GM, Rabl C, Peeva S, Ciovica R, Rao M, Schwarz J-M, Havel P, Schambelan M, Mulligan K. Improvement in Peripheral Glucose Uptake After Gastric Bypass Surgery Is Observed Only After Substantial Weight Loss Has Occurred and Correlates with the Magnitude of Weight Lost. J Gastrointest Surg. 14(1):15-23, 2010.
• Lim JS, Mietus-Snyder M, Valente A, Schwarz J-M, Lustig RH. The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol 7 (5):251-6, 2010.
• Pasarica M, Rood J, Ravussin E, Schwarz J-M, Smith SR, Redman LM. Reduced Oxygenation in Human Obese Adipose Tissue Is Associated with Impaired Insulin Suppression of Lipolysis. J Clin Endocrinol Metab 95(8); 4052-5 2010.
• Rao MN, Mulligan K, Tai V; Wen, MJ; Dyachenko A, Weinberg M, Li X, Lang T; Grunfeld C, Schwarz J-M, Schambelan M. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. J Clin Endocrinol Metab 95(9): 4361-6, 2010.
• Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT; Schwarz J-M; Mulligan K, Schambelan M, Grunfeld C. Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers. J Acquir Immune Defic Syndr 55(3): 361-4, 2010.
• Smith TJ, Schwarz J-M, Montain SJ, Rood J, Pikosky MA, Castaneda-Sceppa C, Glickman E, Young AJ. High protein diet maintains glucose production during exercise-induced energy deficit: a controlled trial. Nutr Metab (Lond). 28;8:26, 2011.
• Stanhope KL, Griffen SC, Bremer AA, Vink RG, Schaefer EJ, Nakajima K, Schwarz J-M, Beysen C, Berglund L, Keim NL, Havel PJ. Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions. Am J Clin Nutr. 94(1):112-9, 2011.
• Cox CL, Stanhope KL, Schwarz J-M, Graham JL, Hatcher B, Griffen SC, Bremer AA, Berglund L, McGahan JP, Keim NL, Havel PJ. Circulating concentrations of monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, and soluble leukocyte adhesion molecule-1 in overweight/obese men and women consuming fructose- or glucose-sweetened beverages for 10 weeks. J Clin Endocrinol Metab. 96(12): E2034-8, 2011.
• Cox CL, Stanhope KL, Schwarz J-M, Graham JL, Hatcher B, Griffen SC, Bremer AA, Berglund L, McGahan JP, Havel PJ, Keim NL.Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women. Eur J Clin Nutr. 66(2):201-8, 2012.